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IL-2 (C145S), Human, Recombinant-1

英文名称:IL-2 (C145S), Human, Recombinant

货号:GPCK021

价格: ¥3880.00 ¥1180.00 ¥420.00 ¥5680.00

规格:
500μg 50μg 10μg 1mg
产品详情
产品规格

500μg / 50μg / 10μg / 1mg

物种

Human

表达宿主

E.coli

PH

Pro22-Thr153 (Cys145Ser)

序列信息

Pro22-Thr153 (Cys145Ser)

检索号

P60568

分子量

15.5 kDa

表观分子量

14 kDa

生物活性

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 90-270 pg/mL.

纯度

> 95% as determined by reducing SDS-PAGE.

内毒素

< 0.1 EU/μg

制剂

Lyophilized from a 0.2 μm filtered solution of 10 mM Acetata-Na, 5% Trehaiose, pH 4.5.

复融

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存条件

Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.

运输条件

Ambient temperature or ice pack.

有效期

12个月

背景介绍

Recombinant Human Interleukin-2 is a highly purified protein with a molecular weight of approximately 15,300 Daltons. The chemical name is des-alanyl-1, serine-145 Human Interleukin-2. It is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the Human IL-2 gene, and the resulting expression clone encodes a modified Human IL-2. This recombinant form differs from native Interleukin-2 in following ways: it is not glycosylated; the molecule has serine substituted for cysteine at amino acid position 145; the aggregation state of molecule is likely to be different from that of native IL-2.

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