
英文名称:VEGFB (N-Fc), Human, Recombinant
货号:GPCK223
价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00
产品详情
500μg / 50μg / 10μg / 1mg
物种Human
表达宿主Human Cells
PHPro22-Ala207
序列信息Pro22-Ala207
检索号P49765
分子量45.7 kDa
表观分子量40&60 kDa
纯度> 95% as determined by reducing SDS-PAGE.
内毒素< 0.1 EU/μg
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件Ambient temperature or ice pack.
有效期12个月
背景介绍VEGFB, as known as VRF, is a member of the VEGF family of Growth Factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane Receptor for semaphorins/collapsins, Ligands involved in neuron guidance.