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VEGFB (N-Fc), Human, Recombinant-1

英文名称:VEGFB (N-Fc), Human, Recombinant

货号:GPCK223

价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00

规格:
500μg 50μg 10μg 1mg
产品详情
产品规格

500μg / 50μg / 10μg / 1mg

物种

Human

表达宿主

Human Cells

PH

Pro22-Ala207

序列信息

Pro22-Ala207

检索号

P49765

分子量

45.7 kDa

表观分子量

40&60 kDa

纯度

> 95% as determined by reducing SDS-PAGE.

内毒素

< 0.1 EU/μg

制剂

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

复融

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存条件

Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.

运输条件

Ambient temperature or ice pack.

有效期

12个月

背景介绍

VEGFB, as known as VRF, is a member of the VEGF family of Growth Factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane Receptor for semaphorins/collapsins, Ligands involved in neuron guidance.

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