
英文名称:FGF-2/bFGF/FGF-b (Met134-Ser288), Human, Recombinant
货号:GPCK008
价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00
产品详情
500μg / 50μg / 10μg / 1mg
物种Human
表达宿主E.coli
PHMet134-Ser288
序列信息Met134-Ser288
检索号P09038
分子量17.3 kDa
表观分子量17 kDa
生物活性Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells. The ED50 for this effect is 0.1-0.6 ng/mL.
纯度> 95% as determined by reducing SDS-PAGE.
内毒素< 0.1 EU/μg
制剂Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 8% Trehalose, 2% Mannitol, 0.05% Tween80, 2 mM EDTA, pH8.0.
复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件Ambient temperature or ice pack.
有效期12个月
背景介绍Fibroblast Growth Factor 2 (FGF2) is a secreted Protein and belongs to the heparin-binding Growth Factors family. FGF2 is produced by epithelial, tumor and other cell types. It involved in developmental processes and regulates differentiation, proliferation, and migration, FGF2 is a critical factor for growing embryonic stem cells in culture without inducing differentiation. FGF2 has a high affinity for heparan sulfate and binding is a step in the FGF basic activation of FGFR tyrosine kinase.
相关文献
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期刊:CURRENT MOLECULAR MEDICINE
DOI:10.2174/1566524023666230324135330
影响因子:2.500
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期刊:APOPTOSIS
DOI:10.1007/s10495-022-01789-y
影响因子:5.600
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