文献(1)
说明书

英文名称:PDGF-BB/PDGF2 (C-6His), Mouse, Recombinant
货号:GPCK068
价格: ¥12880.00 ¥2280.00 ¥780.00 ¥18880.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品形态 | 粉末 |
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | E.coli |
序列信息 | Ser82-Thr190 |
检索号 | AAH53430.1 |
分子量 | 13.4 kDa |
表观分子量 | 15 KDa, reducing conditions |
生物活性 | Measured in a cell proliferation assay using Balb/c3T3 mouse fibroblast cells. The ED50 for this effect is 1.55 ng/mL. |
纯度 | > 95% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of 4 mM HCl. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 4 mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As Growth Factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing. |
相关文献
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期刊:MICROVASCULAR RESEARCH
影响因子:2.9
相关产品: Mouse Brain Microvascular Pericyte Cell Complete Medium, PDGF-BB/PDGF2 (C-6His), Mouse, Recombinant, Mouse Brain Microvascular Pericyte Cells
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