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PDGF-BB/PDGF2 (C-6His), Mouse, Recombinant-1

英文名称:PDGF-BB/PDGF2 (C-6His), Mouse, Recombinant

货号:GPCK068

价格: ¥12880.00 ¥2280.00 ¥780.00 ¥18880.00

规格:
500μg 50μg 10μg 1mg
产品详情

产品信息

产品形态 粉末
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 E.coli
序列信息 Ser82-Thr190
检索号 AAH53430.1
分子量 13.4 kDa
表观分子量 15 KDa, reducing conditions
生物活性 Measured in a cell proliferation assay using Balb/c3T3 mouse fibroblast cells. The ED50 for this effect is 1.55 ng/mL.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 4 mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As Growth Factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.
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