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IGF-I/Somatamedin C/IGF-IA, Mouse, Recombinant-1

英文名称：IGF-I/Somatamedin C/IGF-IA, Mouse, Recombinant

货号：GPCK018

价格： ￥3880.00 ￥380.00 ￥300.00 ￥5680.00

规格：
500μg 50μg 10μg 1mg
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产品信息

产品形态 粉末
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 E.coli
序列信息 MGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKAA with polyhistidine tag at the C-terminus.
检索号 P05017.2
分子量 8.61 kDa
表观分子量 11-17 kDa
标签 His-tag at the C-terminus
生物活性 Measure by its ability to induce MCF-7 cells proliferation. The ED50 for this effect is < 2 ng/mL. The specific activity of recombinant mouse IGF-I is > 5 × 10^5 IU/mg.
纯度 > 98% as determined by SDS-PAGE. Ni-NTA chromatography.
内毒素 < 0.1 EU/μg
制剂 The protein was lyophilized from a 0.2 μm filtered solution containing 1 × PBS, pH 8.0.
复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
储存条件 Lyophilized protein should be stored at -5~-20℃ for 1 year. Upon reconstitution,store at 2-8℃ for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20℃ or -80℃ for 3-6 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure.
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