英文名称：NCI-H1299
货号：GCL-0165
价格： ￥1600.00 ￥1600.00
产品详情
产品信息
| 物种 | Human |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基：RPMI-1640[GPM150110]+10% FBS[163210]+1% P/S[GPB180120] 培养条件： 温度：37℃ |
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
参考资料（来源文献）
| 背景描述 | NCI-H1299细胞来源于一个淋巴结转移，患者接受了初期放疗。NCI-H1299细胞均一性的部分缺失p53蛋白，并缺少p53蛋白表达。NCI-H1299细胞可以合成0.1 pmol/毫克蛋白的NMB蛋白，而不合成促胃液释放肽（GRP）。 |
| 年龄（性别） | 43Y |
| 组织来源 | 肺癌：非小细胞肺癌；转移灶：淋巴结 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肺癌细胞 |
| 生物安全等级 | BSL-1 |
| 基因表达情况 | These cells stain positive for keratin and vimentin but are negative for neurofilament triplet protein. neuromedin B, The cells have a homozygous partial deletion of the p53 protein, and lack expression of p53 protein. The cells produce neuromedin B. |
| 保藏机构 | ATCC; CRL-5803 |
相关文献
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期刊：Nature Communications
DOI：10.1038/s41467-024-55768-9
影响因子：14.7
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The mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy(2025)
期刊：Nature Communications
DOI：10.1038/s41467-025-59309-w
影响因子：14.7
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Chemically engineered antibodies for autophagy-based receptor degradation(2025)
期刊：Nature Chemical Biology
DOI：10.1038/s41589-024-01803-1
影响因子：12.9
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Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression(2025)
期刊：CANCER RESEARCH
DOI：10.1158/0008-5472.CAN-24-3481
影响因子：12.5
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期刊：PHARMACOLOGICAL RESEARCH
DOI：10.1016/j.phrs.2025.107604
影响因子：9.1
相关产品： THP-1 Cells Line, BEAS-2B Cells Line, NCI-H1299 Cells Line, NCI-H226 [H226] Cells Line, NCI-H1975 Cells Line, NCI-H520 Cells Line, PC-9 Cells Line, A549 [A-549] Cells Line, NCI-H1563 Cells Line
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期刊：International Journal of Biological Sciences
影响因子：8.2
相关产品： NCI-H1299 Cells Line, NCI-H292 Cells Line, A549 [A-549] Cells Line, HCC827 Cells Line
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期刊：MATERIALS & DESIGN
DOI：10.1016/j.matdes.2025.114103
影响因子：7.6
相关产品： Calcein AM/PI, NCI-H1299 Cells Line, A549 [A-549] Cells Line
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期刊：BMC Medicine
DOI：10.1186/s12916-025-03926-1
影响因子：7.0
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Discovery of novel dual-target inhibitors of LSD1/EGFR for non-small cell lung cancer therapy(2025)
期刊：ACTA PHARMACOLOGICA SINICA
DOI：10.1038/s41401-024-01439-w
影响因子：6.9
相关产品： NCI-H1299 Cells Line, NCI-H1975 Cells Line, NCI-H460 [H460] Cells Line, PC-9 Cells Line
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期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.4c02724
影响因子：6.8
相关产品： AC16 Cells Line, MCF7 [MCF-7] Cells Line, A549 [A-549] Cells Line, NCI-H1703 Cells Line, DMEM (High glucose) Medium, Hela Cells Line, NCI-H1299 Cells Line, Phosphate Buffer (PBS, 1 ×), NCI-H460 [H460] Cells Line
