
英文名称:GM-CSF/CSF2 (C-6His, Cells), Human, Recombinant
货号:GPCK037
价格: ¥11880.00 ¥2080.00 ¥780.00 ¥17280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | Human Cells |
序列信息 | Ala18-Glu144 |
检索号 | P04141 |
分子量 | 15.5 kDa |
表观分子量 | 17-30 kDa |
标签 | C-6His |
生物活性 | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 6-30 pg/mL. |
纯度 | > 95% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a Growth Factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to Cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a Growth Factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. |
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