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ACVR2A (C-6His), Human, Recombinant-1

英文名称：ACVR2A (C-6His), Human, Recombinant

货号：GPCK106

价格： ￥11880.00 ￥1680.00 ￥580.00 ￥17280.00

规格：
500μg 50μg 10μg 1mg
产品详情

产品信息

产品形态 液体
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Ala20-Pro134
检索号 P27037
分子量 14.35 kDa
表观分子量 28-38 kDa
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Supplied as a 0.2 μm filtered solution of 20 mM PB, 300 mM NaCl, 10% Glycerol, 5% Trealose, pH 7.4.
储存条件 Store at ≤-70℃, stable for 6 months after receipt. Store at ≤-70℃, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件 The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
有效期 6个月
背景介绍 Activin Receptor Type-2A is a Protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activintype 2 Receptor. This gene encodes activin A type II Receptor. Activins are dimeric growth anddifferentiation factors which belong to the transforming Growth Factor-beta (TGF-beta) superfamily ofstructurally related signaling Proteins. Activins signal through a heteromeric complex of Receptor serinekinases which include at least two type I (I and IB) and two type II (II and IIB) Receptors. These Receptors areall transmembrane Proteins, composed of a Ligand-binding extracellular domain with cysteine-rich region, atransmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type IReceptors are essential for signaling; and type II Receptors are required for binding Ligands and forexpression of type I Receptors. Type I and II Receptors form a stable complex after Ligand binding, resultingin phosphorylation of type I Receptors by type II Receptors. Type II Receptors are considered to beconstitutively active kinases.
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