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IL-11/AGIF, Human, Recombinant-1

英文名称:IL-11/AGIF, Human, Recombinant

货号:GPCK361

价格: ¥680.00

规格:
10μg
产品详情

产品信息

产品形态 粉末
产品规格 10μg
表达宿主 E.coli
序列信息 PGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGGLHLTLDWAVRGLLLLKTRL with polyhistidine tag at the N-terminus.
检索号 P20809.1
分子量 19.95 kDa
表观分子量 24 kDa
标签 His-tag at the N-terminus
生物活性 Measure by its ability to induce T11 cells proliferation. The ED50 for this effect is < 0.2 ng/mL. The specific activity of recombinant human IL-11 is approximately > 1 × 10^7 IU/ mg.
纯度 > 98% as determined by SDS-PAGE. Ni-NTA chromatography.
内毒素 < 0.1 EU/μg
制剂 The protein was lyophilized from a 0.2 μm filtered solution containing 1 × PBS, pH 8.0.
复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
储存条件 Lyophilized protein should be stored at -5~-20℃ for 1 year. Upon reconstitution, store at 2-8℃ for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20℃ or -80℃ for 3-6 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 IL-11 is a cytokine and first isolated in 1990 from bone marrow-derived fibrocyte-like stromal cells. It was initially thought to be important for hematopoiesis, notably for megakaryocyte maturation, but subsequently shown to be redundant for platelets, and for other blood cell types, in both mice and humans. It is also known under the names adipogenesis inhibitory factor (AGIF) and was developed as a recombinant protein (rhIL-11) as the drug substance oprelvekin.
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