Purified Anti-Human CD45 Antibody[HI30]
Immunohistochemistry of paraffin-embedded Human tonsil using CD45 Monoclonal Antibody at dilution of 1:100.
货号：GF1137A
价格： ￥400.00 ￥2200.00
产品详情
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Alternate NamesB220;CD45;CD45R;GP180;L-CA;LCA;LY5;T200;PTPRC;CD45 antigen;CD45R0;Ly-5;protein tyrosine phosphatase;receptor type;Receptor-type tyrosine-protein phosphatase C;CD45RO;Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA); T200;c polypeptide;CD 45;homolog of;Leukocyte common antigen;loc;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;protein tyrosine phosphatase;receptor type;C;receptor type C;T200 glycoprotein;T200 leukocyte common antigen;B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Ly-5;LY5;Protein tyrosine phosphatase;receptor type;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200
Swissprot ImmunogenRecombinant Human CD45 protein
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG1, κ
DilutionFCM 2 μg/mL(1×105-5×105 cells)
ConjugateUnconjugated
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date12个月
ShippingIce bag
产品结果图
Immunohistochemistry of paraffin-embedded Human tonsil using CD45 Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Human tonsil using CD45 Monoclonal Antibody at dilution of 1:100.
相关文献
-
CD40 promotes AML survival via non-canonical NF-κB signaling and aberrant lipid metabolism(2025)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2025.114665
影响因子：4.8
相关产品： FITC Anti-Human CD45 Antibody, Cell Cycle (Red Fluorescence), Annexin V-FITC/DAPI, PE Anti-Human CD40 Antibody
-
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-04931-3
影响因子：6.1
相关产品： PE Anti-Human CD11c Antibody, Purified Anti-Human CD45 Antibody, Purified Anti-Human CD3 Antibody, Purified Anti-Mouse CD86 Antibody, Purified Anti-Human CD86 Antibody, Purified Anti-Mouse CD8a Antibody
-
期刊：Drug Design Development and Therapy
影响因子：4.7
相关产品： Purified Anti-Human CD45 Antibody, PE Anti-Human CD105 Antibody, Purified Anti-Human/Mouse CD44 Antibody, Purified Anti-Human CD34 Antibody
-
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2023.102197
影响因子：2.6
相关产品： Tsg101 Antibody, Alix Antibody, CANX Antibody, Hypoxia Inducible Factor-1α Antibody, NOTCH1 Antibody, JAG1 Antibody, VEGF Antibody, CD81 Antibody, Goat Anti-Rabbit IgG(HRP), Purified Anti-Human CD29 Antibody, Purified Anti-Human CD74 Antibody, FITC Anti-Human CD90 Antibody, PE Anti-Human CD105 Antibody, Purified Anti-Human CD34 Antibody, Purified Anti-Human CD45 Antibody