Purified Anti-Human CD86 Antibody[BU63]

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

LAB;ETC;FUN;CTLA-4 Counter-Receptor B;Early T-cell costimulatory molecule;CD28LG;B7-2;B7.2;B70;CD28LG2;LAB72;CD86;Activation B7-2 antigen;BU63;CTLA-4 Counter-Receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN-1;T-lymphocyte activation antigen CD86; B7-2;Activation B7-2 antigen 3;B7 2;B72 antigen;B-lymphocyte activation antigen B7-2;B-lymphocyte activation antigen B7-2 2;CD28 antigen ligand 2;CD28 antigen ligand 2 2;Cd28l2;CD86 antigen;CD86 molecule;CLS1;CTLA-4 counter-receptor B7.2 2;FUN 1;Ly58;Ly-58;MB7;MB7-2;Membrane glycoprotein;MGC34413;TS/A-2

P42081

Recombinant Human CD86 protein

BU63

Mouse

Human

Mouse IgG1, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM;Block

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag