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Purified Anti-Human CD22 Antibody[LL2]

说明书
  • Purified Anti-Human CD22 Antibody[LL2]-1
  • Purified Anti-Human CD22 Antibody[LL2]-2
Purified Anti-Human CD22 Antibody[LL2]-1

货号:GF007540P

价格: ¥700.00 ¥2680.00

规格:
100 μg 1 mg
产品详情
Background

Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.

Alternate Names

Lyb;SIGLEC2FLJ;B-cell receptor CD;T-cell surface antigen Leu;sialic acid binding Ig-like lectin;Sialic acid-binding Ig-like lectin;CD22;SIGLEC-2;SIGLEC2;B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigenMGC130020;CD22 molecule;Lyb-8;sialic acid binding Ig-like lectin 2;Sialic acid-binding Ig-like lectin 2;SIGLEC2FLJ22814;T-cell surface antigen Leu-14;Siglec-2;CD22 molecule;B cell receptor CD22 precursor;B lymphocyte cell adhesion molecule;BL CAM;BLCAM;CD 22;CD22 antigen;CD22 protein;Lectin 2;Leu14;Lyb8;MGC130020;sialic acid binding Ig like lectin 2;Sialic acid binding immunoglobulin like lectin 2;SIGLEC 2;T cell surface antigen Leu 14

Swissprot

P20273

Immunogen

Recombinant Human CD22 protein

Clone No.

LL2

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG2a, κ

Verified Samples

Verified Samples in FCM: Human peripheral blood lymphocytes cell

Dilution

FCM 2 μg/mL(1×105-5×105 cells)

Conjugate

Unconjugated

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiration Date

12个月

Shipping

Ice bag

产品结果图

Purified Anti-Human CD22 Antibody[LL2]-产品结果图-1

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