Purified Anti-Human CD22 Antibody[LL2]
货号:GF007540P
价格: ¥700.00 ¥2680.00
产品详情
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
Alternate NamesLyb;SIGLEC2FLJ;B-cell receptor CD;T-cell surface antigen Leu;sialic acid binding Ig-like lectin;Sialic acid-binding Ig-like lectin;CD22;SIGLEC-2;SIGLEC2;B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigenMGC130020;CD22 molecule;Lyb-8;sialic acid binding Ig-like lectin 2;Sialic acid-binding Ig-like lectin 2;SIGLEC2FLJ22814;T-cell surface antigen Leu-14;Siglec-2;CD22 molecule;B cell receptor CD22 precursor;B lymphocyte cell adhesion molecule;BL CAM;BLCAM;CD 22;CD22 antigen;CD22 protein;Lectin 2;Leu14;Lyb8;MGC130020;sialic acid binding Ig like lectin 2;Sialic acid binding immunoglobulin like lectin 2;SIGLEC 2;T cell surface antigen Leu 14
Swissprot ImmunogenRecombinant Human CD22 protein
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG2a, κ
Verified SamplesVerified Samples in FCM: Human peripheral blood lymphocytes cell
DilutionFCM 2 μg/mL(1×105-5×105 cells)
ConjugateUnconjugated
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date12个月
ShippingIce bag