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IL-2RB/CD122 (C-6His), Human, Recombinant-1

英文名称:IL-2RB/CD122 (C-6His), Human, Recombinant

货号:GPCK151

价格: ¥11880.00 ¥3480.00 ¥1180.00 ¥18880.00

规格:
500μg 50μg 10μg 1mg
产品详情

产品信息

产品形态 粉末
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Ala27-Asp239
检索号 P14784
分子量 25.6 kDa
表观分子量 35-40 kDa
标签 C-6His
生物活性 Loaded Human IL-2RB-His on HIS1K Biosensor, can bind Human IL-2 with an affinity constant of 0.27 μM as determined in BLI assay.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Human IL-2RB, also known asInterleukin-2 Receptor subunit beta,is the Receptor for Interleukin-2. IL2 Receptor complex is involved in Receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 Receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane Protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for Receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family Protein tyrosine kinase although it lacks apparent catalytic Motifs.
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