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IL-1RAcP/IL-1R3/IL-1F6 (C-6His), Human, Recombinant-1

英文名称：IL-1RAcP/IL-1R3/IL-1F6 (C-6His), Human, Recombinant

货号：GPCK142

价格： ￥6080.00 ￥980.00 ￥320.00 ￥8680.00

规格：
500μg 50μg 10μg 1mg
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产品信息

产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Ser21-Gln356
检索号 Q9NPH3-2
分子量 39.75 kDa
表观分子量 50-70 kDa
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the Interleukin-1 Receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-Ligand binding accessory component of the Receptors for IL1α, IL1βand IL33. IL-1RAcP mediates Interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 Receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to Interleukins by associating with soluble IL1R1 and enhancing Interleukin-binding to the decoy Receptor.
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