请输入关键词！

说明书
一键复制产品信息
IL-17A/CTLA8 (C-6His), Human, Recombinant-1

英文名称：IL-17A/CTLA8 (C-6His), Human, Recombinant

货号：GPCK178

价格： ￥11880.00 ￥1880.00 ￥780.00 ￥17280.00

规格：
500μg 50μg 10μg 1mg
产品详情

产品信息

产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Gly24-Ala155
检索号 Q16552
分子量 15.9 KDa
表观分子量 15-22 KDa
标签 C-6His
生物活性 Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1-10 ng/mL.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Interleukin-17 is a potent pro-inflammatory Cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This Cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of Interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
产品推荐
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
联系我们
sales@procell.com.cn
400-999-2100
相关推荐
×
确定