
英文名称:FGF-17 (C-6His), Human, Recombinant
货号:GPCK130
价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00
产品详情
500μg / 50μg / 10μg / 1mg
物种Human
表达宿主Human Cells
PHThr23-Thr216
序列信息Thr23-Thr216
检索号O60258
分子量22.6 kDa
表观分子量31 kDa
标签C-6His
生物活性Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 2.1 μg/mL.
纯度> 95% as determined by reducing SDS-PAGE.
内毒素< 0.1 EU/μg
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件Ambient temperature or ice pack.
有效期12个月
背景介绍Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding Growth Factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition, FGF17 stimulates the proliferation and activation of cells that express FGF Receptors.