请输入关键词！

说明书
一键复制产品信息
FGF-1/FGFa/FGF-acidic (Phe16-Asp155), Human, Recombinant-1

英文名称：FGF-1/FGFa/FGF-acidic (Phe16-Asp155), Human, Recombinant

货号：GPCK004

价格： ￥3480.00 ￥1080.00 ￥420.00 ￥4880.00

规格：
500μg 50μg 10μg 1mg
产品详情

产品信息

产品形态 粉末
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 E.coli
序列信息 Phe16-Asp155
检索号 P05230
分子量 16 kDa
表观分子量 16 kDa
生物活性 Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 0.2-2 ng/mL.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 50 mM MOPS, 100 mM Na2SO4, 1 mM EDTA, pH 7.9.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding Growth Factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF Receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
产品推荐
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
-产品推荐-3
联系我们
sales@procell.com.cn
400-999-2100
相关推荐
×
确定