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Activin A, Human/Mouse/Rat, Recombinant-1

英文名称：Activin A, Human/Mouse/Rat, Recombinant

货号：GPCK270

价格： ￥2480.00 ￥680.00

规格：
50μg 10μg
产品详情

产品信息

产品规格 50μg / 10μg
表达宿主 E.coli
序列信息 MGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS with polyhistidine tag at the C-terminus.
检索号 P08476 (Human), Q04998 (Mouse), P18331 (Rat)
分子量 13.9 kDa
表观分子量 15 kDa
标签 His-tag at the C-terminus
生物活性 Measure by its ability to induce hemoglobin expression in K562 cells.The ED50 for this effect is < 0.85 ng/mL. The specific activity of recombinant human Activin A is approximately > 1.4 × 10^3 IU/mg.
纯度 > 95% as determined by SDS-PAGE. Ni-NTA chromatography.
内毒素 < 0.1 EU/μg
制剂 The protein was lyophilized from a 0.2 μm filtered solution containing 0.1% sarkosyl in 1 × PBS, pH 8.0.
复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
储存条件 Lyophilized protein should be stored at -5~-20℃ for 1 year. Upon reconstitution, store at 2-8℃ for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20℃ or -80℃ for 3-6 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.
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