
英文名称:TNF-α/TNFA/TNFSF2, Rabbit, Recombinant
货号:GPCK056
价格: ¥11880.00 ¥2780.00 ¥880.00 ¥17280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | E.coli |
序列信息 | Val78-Leu235 |
检索号 | P04924 |
分子量 | 17.59 kDa |
表观分子量 | 18 kDa |
生物活性 | Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 3.5 pg/mL. |
纯度 | > 95% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.4. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Tumor necrosis factor alpha (TNFα) is the prototypic Ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of Receptors TNF-R1 (TNF Receptor type 1,p55R) and TNF-R2 (TNF Receptor type 2,p75R). TNFα is a pleiotropic Cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. |
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