英文名称:SW620
货号:GCL-0225
价格: ¥1600.00 ¥1600.00
产品详情
产品信息
物种 | Human |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 |
冻存液:无血清非程序冻存液(GPB180438)/通用血清型程序冻存液(GPB180436) 温度:液氮 |
培养方案A(默认) |
生长培养基:Leibovitz's L-15[GPM151010]+10% FBS[163210]+1% P/S[GPB180120] 培养条件: 温度:37℃ |
培养方案B(可选) |
生长培养基:DMEM[GPM150210]+10% FBS[163210]+1% P/S[GPB180120] 培养条件: 温度:37℃ |
推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
注意事项 |
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参考资料(来源文献)
背景描述 | SW620细胞是从一个51岁男性白人组织中分离得到的,由A·Leibovitz等从一个淋巴结建株。SW620细胞主要由无绒毛的小园球细胞和双极细胞组成;SW620细胞仅合成少量癌胚抗原(CEA),在裸鼠中有高度的致瘤性。 |
年龄(性别) | 51Y |
组织来源 | 结直肠腺癌,来自转移淋巴结 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肠癌细胞 |
生物安全等级 | BSL-1 |
抗原表达情况 | Blood Type A; Rh+ |
基因表达情况 | Carcinoembryonic antigen (CEA) 0.15 ng/10⁶ cells/10 days; transforming growth factor alpha; matrilysin. The cells are negative for expression of CSAp (CSAp-) and colon antigen 3, negative. The cells are positive for keratin by immunoperoxidase staining. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10⁷ cells). |
保藏机构 | ATCC; CCL-227 ECACC; 87051203 |
相关文献
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期刊:Bioengineered
DOI:10.1080/21655979.2020.1757224
影响因子:4.900
相关产品: SW620 Cells Line, SW480 [SW-480] Cells Line, Caco-2 Cells Line, LoVo Cells Line, 293T [HEK-293T] Cells Line, Ham's F-12K
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期刊:Drug Design Development and Therapy
影响因子:4.800
相关产品: HCT 116 Cells Line, SW620 Cells Line, HT-29 Cells Line, McCoy's 5A, SW620(DMEM Cells Line, McCoy's 5A Medium
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期刊:Investigational New Drugs
DOI:10.1007/s10637-020-01014-0
影响因子:3.400
相关产品: HCT 116 Cells Line, SW480 [SW-480] Cells Line, SW620 Cells Line, HT-29 Cells Line, LoVo Cells Line, RKO Cells Line
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期刊:Cancer Management and Research
影响因子:3.300
相关产品: HCT 116 Cells Line, SW620 Cells Line, HCT 116 Cells Complete Medium,
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期刊:Journal of Nanoscience and Nanotechnology
影响因子:
相关产品: SW620 Cells Line
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期刊:Cancer Letters
DOI:10.1016/j.canlet.2019.04.014
影响因子:9.700
相关产品: SW480 [SW-480] Cells Line, SW620 Cells Line, HCT 116 Cells Line, HT-29 Cells Line, RKO Cells Line, LoVo Cells Line
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期刊:International Journal of Biological Macromolecules
DOI:10.1016/j.ijbiomac.2019.07.117
影响因子:8.200
相关产品: LoVo Cells Line, SW620 Cells Line
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A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer(2019)
期刊:Cancer Cell International
影响因子:5.800
相关产品: HCT 116 Cells Line, SW480 [SW-480] Cells Line, SW620 Cells Line
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SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway(2019)
期刊:Clinical And Experimental Pharmacology And Physiology
影响因子:2.900
相关产品: SW480 [SW-480] Cells Line, SW620 Cells Line, HCT 116 Cells Line, COLO 205 Cells Line, LoVo Cells Line
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miRNA-101通过靶向CDK8调控结肠癌细胞侵袭和Wnt/β-catenin通路活化(2018)
期刊:肿瘤防治研究
DOI:10.3971/j.issn.1000-8578.2018.17.1558
影响因子:0.700
相关产品: HCT 116 Cells Line, HT-29 Cells Line, LoVo Cells Line, SW620 Cells Line, COLO 205 Cells Line