英文名称:SW620
货号:GCL-0225
价格: ¥1600.00 ¥1600.00
产品详情
产品信息
物种 | Human |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 |
冻存液:55% 基础培养基+40% FBS+5% DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:Leibovitz's L-15[GPM151010]+10% FBS[163210]+1% P/S[GPB180120] 培养条件: 温度:37℃ |
培养方案B(可选) |
生长培养基:DMEM[GPM150210]+10% FBS[163210]+1% P/S[GPB180120] 培养条件: 温度:37℃ |
推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
注意事项 |
|
参考资料(来源文献)
背景描述 | SW620细胞是从一个51岁男性白人组织中分离得到的,由A·Leibovitz等从一个淋巴结建株。SW620细胞主要由无绒毛的小园球细胞和双极细胞组成;SW620细胞仅合成少量癌胚抗原(CEA),在裸鼠中有高度的致瘤性。 |
年龄(性别) | 51Y |
组织来源 | 结直肠腺癌,来自转移淋巴结 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肠癌细胞 |
生物安全等级 | BSL-1 |
抗原表达情况 | Blood Type A; Rh+ |
基因表达情况 | Carcinoembryonic antigen (CEA) 0.15 ng/10⁶ cells/10 days; transforming growth factor alpha; matrilysin. The cells are negative for expression of CSAp (CSAp-) and colon antigen 3, negative. The cells are positive for keratin by immunoperoxidase staining. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10⁷ cells). |
保藏机构 | ATCC; CCL-227 ECACC; 87051203 |
相关文献
-
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-025-03277-y
影响因子:11.4
相关产品: DLD-1 Cells Line, HCT 116 Cells Line, Caco-2 Cells Line, SW620 Cells Line, SW48 Cells Line, MEM Medium, SW480 [SW-480] Cells Line, DMEM (High glucose) Complete Medium (10)
-
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2025.1596451
影响因子:5.7
相关产品: HT-29 Cells Line, HCT 116 Cells Line, NCM460 Cells Line, Caco-2 Cells Line, DLD-1 Cells Line, SW480 [SW-480] Cells Line, SW620 Cells Line
-
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2025.1571135
影响因子:4.4
相关产品: SW620 Cells Line, MDA-MB-231 Cells Line, NCI-H1975 Cells Line, 4T1 Cells Line, HK-2 Cells Line
-
Discovery of the novel celastrol-based PROTACs for the treatment of non-small cell lung cancer(2025)
期刊:MOLECULAR DIVERSITY
DOI:10.1007/s11030-025-11140-7
影响因子:3.9
相关产品: NCI-H358 Cells Line, MCF7 [MCF-7] Cells Line, NCI-H1975 Cells Line, Annexin V-FITC/PI Apoptosis Kit, HBZY-1 Cells Line, SW620 Cells Line
-
期刊:BMC CANCER
DOI:10.1186/s12885-025-13873-y
影响因子:3.4
相关产品: LoVo Cells Line, SW480 [SW-480] Cells Line, NCM460 Cells Line, HT-29 Cells Line, SW620 Cells Line, CT26.WT Cells Line, HCT 116 Cells Line
-
期刊:BMC CANCER
DOI:10.1186/s12885-025-14357-9
影响因子:3.4
相关产品: Human Colonic Smooth Muscle Cell Complete Medium, SW620 Cells Line, Human Peripheral Blood Mononuclear Cell Complete Medium, SW480 [SW-480] Cells Line, Human Colonic Smooth Muscle Cells, Human Colonic Mucosal Epithelial Cells, Human Colonic Mucosal Epithelial Cell Complete Medium, Human Peripheral Blood Mononuclear Cells
-
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-025-02775-1
影响因子:3.4
相关产品: SW620 Cells Line
-
期刊:Journal of Cancer
影响因子:3.3
相关产品: SW480 [SW-480] Cells Line, HCT 116 Cells Line, SW620 Cells Line, HT-29 Cells Line, HCT-8 [HRT-18] Cells Line, LoVo Cells Line
-
METTL1 Enhances RRP9 mRNA Stability Through m7G Modification to Drive Colorectal Tumorigenesis(2025)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23892
影响因子:3.0
相关产品: LoVo Cells Line, SW620 Cells Line
-
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-025-02635-2
影响因子:2.8
相关产品: HT-29 Cells Line, COLO 205 Cells Line, THP-1 Cells Line, SW620 Cells Line, HCT-8 [HRT-18] Cells Line, HCT 116 Cells Line