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ST2/IL1RL1, Human, Recombinant-1

英文名称:ST2/IL1RL1, Human, Recombinant

货号:GPCK167

价格: ¥5080.00 ¥780.00 ¥420.00 ¥8280.00

规格:
500μg 50μg 10μg 1mg
产品详情
产品规格

500μg / 50μg / 10μg / 1mg

物种

Human

表达宿主

Human Cells

PH

Lys19-Phe328

序列信息

Lys19-Phe328

检索号

Q01638-2

分子量

36.0 kDa

表观分子量

60 kDa

标签

C-6His

生物活性

Immobilized Human ST2-His at 5 μg/mL (100 μL/well) can bind Human IL-33-His. The ED50 of Human IL-33-His is 8.44 ng/mL.

纯度

> 95% as determined by reducing SDS-PAGE.

内毒素

< 0.1 EU/μg

制剂

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

复融

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存条件

Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.

运输条件

Ambient temperature or ice pack.

有效期

12个月

背景介绍

Interleukin 1 Receptor-like 1 (IL1RL1) is a member of the Interleukin-1 Receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a Receptor for Interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 Cytokine production, it directly implicated in the progression of cardiac disease.

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