
英文名称:ST2/IL1RL1, Human, Recombinant
货号:GPCK167
价格: ¥5080.00 ¥780.00 ¥420.00 ¥8280.00
产品详情
500μg / 50μg / 10μg / 1mg
物种Human
表达宿主Human Cells
PHLys19-Phe328
序列信息Lys19-Phe328
检索号Q01638-2
分子量36.0 kDa
表观分子量60 kDa
标签C-6His
生物活性Immobilized Human ST2-His at 5 μg/mL (100 μL/well) can bind Human IL-33-His. The ED50 of Human IL-33-His is 8.44 ng/mL.
纯度> 95% as determined by reducing SDS-PAGE.
内毒素< 0.1 EU/μg
制剂Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件Ambient temperature or ice pack.
有效期12个月
背景介绍Interleukin 1 Receptor-like 1 (IL1RL1) is a member of the Interleukin-1 Receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a Receptor for Interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 Cytokine production, it directly implicated in the progression of cardiac disease.