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TNFR2/TNFRSF1B/CD120b (C-6His), Human, Recombinant-1

英文名称：TNFR2/TNFRSF1B/CD120b (C-6His), Human, Recombinant

货号：GPCK221

价格： ￥11880.00 ￥2280.00 ￥780.00 ￥17280.00

规格：
500μg 50μg 10μg 1mg
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产品信息

产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Leu23-Asp257
检索号 P20333
分子量 26.2 kDa
表观分子量 40 kDa
生物活性 Immobilized Recombinant Human TNF alpha at 5 μg/mL (100 μL/well) can bind Recombinant Human TNF RII (C-6His). The ED50 of Recombinant Human TNF RII (C-6His) (CI39) is 0.212 μg/mL.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Tumor necrosis factor Receptor superfamily member 1B is a 461 amino acids Protein that belongs to the TNFR (tumor necrosis factor Receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This Receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
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