Purified Anti-Human/Mouse KLRG-1 Antibody[2F1]

Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8⁺and CD4⁺cells, including CD4⁺and CD8⁺effector/memory cells, potent regulatory CD4⁺T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

2F1-Ag;MAFA

Q96E93, O88713

Recombinant Mouse KLRG-1 protein

2F1

Syrian Hamster

Human;Mouse

Syrian Hamster IgG

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag