
英文名称:IL-15RA/CD215 (C-Fc), Mouse, Recombinant
货号:GPCK242
价格: ¥5080.00 ¥780.00 ¥420.00 ¥8280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | Human Cells |
序列信息 | Gly33-Lys205 |
检索号 | Q60819 |
分子量 | 45.5 kDa |
表观分子量 | 60-90 kDa |
标签 | C-Fc |
生物活性 | Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/mL. |
纯度 | > 90% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Mouse Interleukin-15 Receptor subunit alpha, also known as Il15ra, is a high-affinity Receptor for Interleukin-15. Il15ra associates as a heterotrimer with the IL-2 Receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the Receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons. |
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