
英文名称:MIP-4/CCL18 (N-6His), Human, Recombinant
货号:GPCK110
价格: ¥12880.00 ¥3480.00 ¥1180.00 ¥18880.00
产品详情
500μg / 50μg / 10μg / 1mg
物种Human
表达宿主E.coli
PHAla21-Ala89
序列信息Ala21-Ala89
检索号P55774
分子量10.1 kDa
表观分子量13 kDa
标签N-6His
纯度> 95% as determined by reducing SDS-PAGE.
内毒素< 0.1 EU/μg
制剂Lyophilized from a 0.2 μm filtered solution of 20 mM Citrate, 6% Trehalose, 4% Mannitol, 0.05% Tween 80, pH 4.0.
复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件Ambient temperature or ice pack.
有效期12个月
背景介绍C-C Motif Chemokine 18 (CCL18) is secreted Protein that belongs to the intercrine beta (Chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.