
英文名称:FGF-21/FGFL, Human, Recombinant
货号:GPCK132
价格: ¥11880.00 ¥1680.00 ¥580.00 ¥17280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | E.coli |
序列信息 | MHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS with polyhistidine tag at the C-terminus. |
检索号 | Q9NSA1.1 |
分子量 | 20.35 kDa |
表观分子量 | 25 kDa |
标签 | His-tag at the C-terminus |
生物活性 | Measure by its ability to induce proliferation in BaF3 cells transfected with human FGFRIIIc. The ED50 for this effect is < 0.4 μg/mL. |
纯度 | > 98% as determined by SDS-PAGE. Ni-NTA chromatography. |
内毒素 | < 0.1 EU/μg |
制剂 | The protein was lyophilized from a 0.2 μm filtered solution containing 1 × PBS, pH 8.0. |
复融 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein. |
储存条件 | Lyophilized protein should be stored at -5~-20℃ for 1 year. Upon reconstitution,store at 2-8℃ for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20℃ or -80℃ for 3-6 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | FGF-21 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 is produced by hepatocytes in response to free fatty acid (FFA) stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestion of a high-fat/low-carbohydrate diet. Upon FGF-21 secretion, white adipose tissue is induced to release FFAs from triglyceride stores. Once FFAs reach hepatocytes, they are oxidized and reduced to acetyl-CoA. |
产品推荐
相关推荐
• HDGF, Mouse, Recombinant
• FGF-1/FGFa/FGF-acidic (Ala2-Asp155), Human, Recombinant
• TRAIL/TNFSF10/TL2/Apo2L/CD253, Mouse, Recombinant
• IL-31, Human, Recombinant
• IL-4Rα/CD124 (C-Fc), Human, Recombinant
• IL-2 (C-6His), Human, Recombinant
• IL-10/B-TCGF/CSIF/TGIF, Mouse, Recombinant
• FGF-12/FHF-1, Human, Recombinant
• BMP-15/GDF-9B/ODG2/POF4, Human, Recombinant
• MMP7/MPSL1/PUMP-1, Human, Recombinant
×