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M-CSF/CSF1, Rat, Recombinant-1

英文名称:M-CSF/CSF1, Rat, Recombinant

货号:GPCK044

价格: ¥11880.00 ¥3480.00 ¥1180.00 ¥18880.00

规格:
500μg 50μg 10μg 1mg
产品详情
产品规格

500μg / 50μg / 10μg / 1mg

物种

Rat

表达宿主

Human Cells

PH

Glu33-Arg254

序列信息

Glu33-Arg254

检索号

Q8JZQ0

分子量

25.2 kDa

表观分子量

46 kDa

纯度

> 95% as determined by reducing SDS-PAGE.

内毒素

< 0.1 EU/μg

制剂

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

复融

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存条件

Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.

运输条件

Ambient temperature or ice pack.

有效期

12个月

背景介绍

Rat Macrophage colony-stimulating factor 1 (MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic Growth Factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipo Protein clearance.

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