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GRO-α/CXCL1 (C-6His), Mouse, Recombinant-1

英文名称:GRO-α/CXCL1 (C-6His), Mouse, Recombinant

货号:GPCK234

价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00

规格:
500μg 50μg 10μg 1mg
产品详情

产品信息

产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Arg20-Lys96
检索号 P12850
分子量 9.4 kDa
表观分子量 11-13 kDa
标签 C-6His
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Growth-regulated alpha Protein (CXCL1,KC), is a member of the alpha Chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-Derived Growth Factor. The N-terminal processed form KC (5-72) of the Protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the orthologs of the human GROs and rat CINCs. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory Chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.
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