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Flt-3L/Flt3LG (C-6His), Human, Recombinant-1

英文名称：Flt-3L/Flt3LG (C-6His), Human, Recombinant

货号：GPCK090

价格： ￥11880.00 ￥2280.00 ￥780.00 ￥17280.00

规格：
500μg 50μg 10μg 1mg
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产品信息

产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 Human Cells
序列信息 Thr27-Pro184
检索号 P49771
分子量 19 kDa
表观分子量 24-32 kDa
标签 C-6His
生物活性 Immobilized Human FLT3LG (C-6His) 5 μg/mL (100 μL/well) can bind Human FLT3 (C-Fc). The EC50 of Human FLT3 (C-Fc) is not higher than 10 ng/mL.
纯度 > 95% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle Cytokine. Mature human Flt-3 Ligand consists of a extracellular domain (ECD) with a Cytokine-like domain and a juxtamembrane tether region, a transmembrane segment, and a cytoplasmic tail. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other Growth Factors, Flt3 Ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 Receptor.
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