AF/LE Purified Anti-Mouse/Human CD11b Antibody[M1/70]

文献(4) 说明书

C57/BL6 Mouse bone marrow cells were stained with 0.2 μg AF/LE Purified Anti-Mouse/Human CD11b Antibody[M1/70] (Right) and 0.2 μg Rat IgG2b, κ Isotype Control (Left), followed by PE-conjugated Goat Anti-Rat IgG Secondary Antibody.

货号：GF10810

规格：

100 μg 1 mg

产品详情

Background

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Alternate Names

CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1

Swissprot

P05555, P11215

Immunogen

Recombinant Mouse CD11b protein

Clone No.

M1/70

Host

Rat

Reactivity

Human;Mouse

Isotype

Rat IgG2b, κ

Dilution

FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag