PE Anti-Mouse CD105 Antibody[MJ7/18]

文献(2) 说明书

货号：GFH1233UD

规格：

100 μg 25 μg

产品详情

Background

CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

Alternate Names

END;Endoglin;Eng

Clone No.

MJ7/18

Host

Rat

Reactivity

Mouse

Isotype

Rat IgG2a, κ

Conjugate

Concentration

0.2 mg/mL

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

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联系我们

sales@procell.com.cn

400-999-2100

PE Anti-Mouse CD105 Antibody[MJ7/18]

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