Recombinant Rat IL-6 Protein

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货号：GPMR0077

规格：

500 μg 100 μg 20 μg 1 mg

产品详情

Abbre

IL-6

Alternate Names

BSF;IFNB;BSF2;CDF;HGF;HSF;IFNB2;Interleukin-6;Il6;Il 6;Interleukin 6;Il-6

Calculated Mw

24 kDa

Observed Mw

28 kDa

Swissprot

P20607

Background

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.

Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.