Recombinant Mouse PDGF-BB Protein(Sumo Tag)

说明书

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Recombinant Mouse PDGF-BB Protein(Sumo Tag)-1

货号：GPEM0184

规格：

500 μg 100 μg 20 μg 1 mg

产品详情

Abbre

PDGF-BB

Alternate Names

Sis;Pdgfb;Becaplermin;c-sis;PDGF Subunit B;PDGF2;PDGF-2;PDGFBB;Platelet-Derived Growth Factor B Chain;Platelet-Derived Growth Factor Beta Polypeptide;Platelet-Derived Growth Factor Subunit B;Proto-Oncogene c-Sis;SSV

Calculated Mw

24.8 kDa

Observed Mw

33 kDa

Swissprot

P31240

Background

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.

Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.