Recombinant Human G-CSF R/CD114 Protein(His Tag)

G-CSF R/CD114

SCN;CSF3R;CD114;GCSFR;SCN7;Csfgr;CD114 antigen;colony stimulating factor 3 receptor (granulocyte);G-CSF R;G-CSF receptor;G-CSFR;GCSFRG-CSF-R;CSF-3R

65.6 kDa

85-90 kDa

Q99062

Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, the protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.