Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

Pdl;B7h;B7 homolog;PDCD1 ligand;programmed death ligand;Programmed cell death ligand;programmed cell death 1 ligand;Programmed cell death 1 ligand 1Cd;PD-L;Pdcd1lg;PD-;B7h1;Pdl1;Pdcd1l;Pdcd1l1;Pdcd1lg1;A530045L16Rik;B7-H1;B7 homolog 1;B7-H;PDCD1 ligand 1;PD-L1;programmed cell death 1 ligand 1;Programmed cell death 1 ligand 1Cd274;Programmed cell death ligand 1;programmed death ligand 1;Cd274; PDL1;A530045L16Rik;B7h1;Pdcd1l;Pdcd1l1;Pdcd1lg1

Q9EP73

Recombinant Mouse CD274/PD-L1 protein

10F.9G2

Rat

Mouse

Rat IgG2b, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag