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PE Anti-Human CD194/CCR4 Antibody[L291H4]

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  • PE Anti-Human CD194/CCR4 Antibody[L291H4]-1
PE Anti-Human CD194/CCR4 Antibody[L291H4]-1

货号:GFH1366D

价格: ¥3528.00 ¥1200.00 ¥6048.00

规格:
100 Tests 20 Tests 100 Tests × 2
产品详情
Background

CD194, also known as CCR4, is a CC chemokine receptor. It binds CCL17 and CCL22 and is expressed on a subset of T and B cells, basophils, monocytes, and NK cells. Human Th2 cells are characterized by the expression of CCR4 and CCR8, and these receptors are regulated differently during Th2 development. Human peripheral blood Tregs can be divided into two distinct populations based on the expression of CCR4. Freshly isolated Tregs express CCR4 and presumably represent memory-type Tregs, and CCR4- Tregs require CD3-mediated activation to acquire a regulatory activity. Depletion of CCR4+ T cells leads to Th1-type polarization of CD4+ T cells and augmentation of CD8+ T cell responses to tumor antigens. CCR4 and its ligands are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases.

Alternate Names

CC-CKR-4;CKR4;CMKBR4;ChemR13;HGCN:14099;K5-5;MGC88293

Swissprot

P51679

Clone No.

L291H4

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG1, κ

Conjugate

PE

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

Storage

This product can be stored at 2-8°C for 12 months. Do not freeze.

Expiration Date

12个月

Shipping

冰袋

产品结果图

PE Anti-Human CD194/CCR4 Antibody[L291H4]-产品结果图-1

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