Purified Anti-Human CD42b Antibody[HIP1]

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

DBPLT;GP1BA;BDPLT1;BDPLT3;BSS;CD42B;CD42b-alpha;DBPLT3;GP1B;GPIbA;GPIbalpha;VWDP;Carbohydrate-Rich Portion of Platelet Membrane Glycoprotein Ib Alpha Polypeptide;Antigen CD42b alpha;CD 42b;CD42b alpha;CD42b antigen;GLYCOCALICIN;Glycoprotein Ib (platelet) alpha polypeptide;Glycoprotein Ibalpha;GP Ib alpha;GPIb alpha;MGC34595;Platelet glycoprotein Ib alpha chain;Platelet glycoprotein Ib alpha polypeptide;Platelet membrane glycoprotein 1b alpha subunit

P07359

Recombinant Human CD42b protein

HIP1

Mouse

Human

Mouse IgG1,κ

Verified Samples in FCM: Human peripheral blood platelet cell

FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag