AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

hPD;mPD;Programmed Death;Programmed cell death;Programmed cell death protein;PDCD;hSLE;SLEB;PD-1;CD279;hPD-1;hPD-l;hSLE1;mPD-1;Programmed cell death 1;Programmed cell death protein 1;Programmed Death-1;SLEB2;Pd1;Pdcd1;CD279 antigen;hPD 1;hPD l;Ly101;PD 1;Pdc1;PDCD 1;Programmed cell death 1 protein;Protein PD 1;Protein PD-1;Systemic lupus erythematosus susceptibility 2

Q02242

Recombinant Mouse CD279 protein

29F.1A12

Rat

Mouse

Rat IgG2a, κ

Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD279 gene

FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

None (AF/LE)

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag