APC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

文献(2) 说明书

货号：GFH1229E

规格：

100 Tests 20 Tests 100 Tests × 2

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Background

Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

Alternate Names

PD1;PDCD1;Protein PD-1;hPD-1

Swissprot

Q15116

Clone No.

EH12.2H7

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG1, κ

Conjugate

APC

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

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联系我们

sales@procell.com.cn

400-999-2100

APC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

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