PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with PE Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
货号:GFH1133D
价格: ¥2448.00 ¥1080.00 ¥3744.00
产品详情
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG2b, κ
ConjugatePE
Concentration5 μL/Test
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with PE Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with PE Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
相关文献
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期刊:Oncogenesis
DOI:10.1038/s41389-023-00500-3
影响因子:6.2
相关产品: PE Anti-Human CD274/PD-L1 Antibody, APC Anti-Human CD273/PD-L2 Antibody
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期刊:Genes
影响因子:3.5
相关产品: PE Anti-Human CD274/PD-L1 Antibody, APC Anti-Human CD273/PD-L2 Antibody
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期刊:Cell Reports
DOI:10.1016/j.celrep.2019.10.093
影响因子:7.815
相关产品: PE Anti-Human CD274/PD-L1 Antibody, APC Anti-Human CD273/PD-L2 Antibody, PE Anti-Human CD3 Antibody, FITC Anti-Human CD8a Antibody