
英文名称:PDGF-BB/PDGF2, Human, Recombinant
货号:GPCK067
价格: ¥11880.00 ¥3480.00 ¥1180.00 ¥17280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | E.coli |
序列信息 | Ser82-Thr190 |
检索号 | P01127 |
分子量 | 12.42 kDa |
表观分子量 | 14 kDa |
生物活性 | Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/mL. |
纯度 | > 95% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20 mM NaAC-HAC, 4% Mannitol, pH 4.5. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its Receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. |
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