英文名称:NIH:OVCAR-3 [OVCAR3]
货号:GCL-0178
价格: ¥2000.00 ¥2000.00
产品详情
产品信息
物种 | Human |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 |
冻存液:55% 基础培养基+40% FBS+5% DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:RPMI-1640[GPM150110]+20% FBS[163210]+10 μg/mL Insulin[GPB180432]+1% P/S[GPB180120] 培养条件: 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
参考资料(来源文献)
背景描述 | NIH:OVCAR-3 [OVCAR3]细胞是由T·C·Hamilton在1982年建系,NIH:OVCAR-3 [OVCAR3]细胞取材于患进行性卵巢腺癌病人的恶性腹水。在裸鼠皮下接种 1×10⁷细胞,21天后全部成瘤。NIH:OVCAR-3 [OVCAR3]细胞是研究卵巢癌药物抗性的一个合适的模型系统且由于存在激素受体,这对于激素治疗的评估或许是有用的。 |
年龄(性别) | 60Y |
组织来源 | 卵巢腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 卵巢癌细胞 |
生物安全等级 | BSL-1 |
致瘤性 | Yes, Forms colonies in soft agar. Yes, in nude mice inoculated subcutaneously with 1×10⁷ cells (Tumors developed within 21 days at 100% frequency (5/5)). |
受体表达情况 | Androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive |
保藏机构 | ATCC; HTB-161 |
相关文献
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期刊:Discover Oncology
DOI:10.1007/s12672-023-00815-y
影响因子:2.2
-
MOB kinase activator 1A acts as an oncogene by targeting PI3K/AKT/mTOR in ovarian cancer(2023)
期刊:Discover Oncology
DOI:10.1007/s12672-023-00705-3
影响因子:2.2
相关产品: IOSE80 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, SK-OV-3 Cells Line
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circ_0025033 promotes ovarian cancer development via regulating the hsa_miR-370-3p/SLC1A5 axis(2022)
期刊:CELLULAR & MOLECULAR BIOLOGY LETTERS
DOI:10.1186/s11658-022-00364-2
影响因子:8.700
相关产品: Hey Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, Human Umbilical Vein Endothelial cells, Human Umbilical Vein Endothelial cells Complete Medium
-
期刊:Oxidative Medicine and Cellular Longevity
影响因子:7.300
相关产品: A2780 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, ES-2 Cells Line, RPMI-1640, Fetal Bovine Serum, McCoy's 5A, Enhanced Cell Counting Kit 8 (WST-8/CCK8), PI Reagent (50μg/mL)
-
期刊:Oncology Letters
影响因子:3.100
-
期刊:Reproductive Biology
DOI:10.1016/j.repbio.2022.100704
影响因子:2.100
相关产品: SK-OV-3 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, A2780 Cells Line, ES-2 Cells Line, 293T [HEK-293T] Cells Line, RPMI-1640, Fetal Bovine Serum, Penicillin-Streptomycin Solution, 100×
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期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.111533
影响因子:7.500
相关产品: CoC1 Cells Line, SK-OV-3 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, RPMI-1640, McCoy's 5A
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期刊:Cell Cycle
DOI:10.1080/15384101.2021.1963910
影响因子:5.200
相关产品: OV-90 Cells Line, A2780 Cells Line, SK-OV-3 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, Human Ovarian Epithelial cells, NIH:OVCAR-3 [OVCAR3] Cells Complete Medium, Human Ovarian Epithelial cells Complete Medium, OV-90 Cells Complete Medium
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期刊:Gynecologic Oncology
DOI:10.1016/j.ygyno.2021.04.013
影响因子:4.700
相关产品: A2780 Cells Line, Human Ovarian Epithelial cells, SK-OV-3 Cells Line, ES-2 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line
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CircLNPEP promotes the progression of ovarian cancer through regulating miR-876-3p/ WNT5A axis(2021)
期刊:Cell Cycle
DOI:10.1080/15384101.2021.1965723
影响因子:4.300
相关产品: A2780 Cells Line, SK-OV-3 Cells Line, NIH:OVCAR-3 [OVCAR3] Cells Line, SK-BR-3 [SKBR3] Cells Line