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• Drug repurposing of fostamatinib against cancer via potential cytotoxicity and immune checkpoint regulation(2025)

  期刊：Frontiers in Immunology

  DOI：10.3389/fimmu.2025.1602189

  影响因子：5.7

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• Venetoclax synergizes with Wnt/β-catenin inhibitor C-82 in acute myeloid leukemia by increasing the degradation of Mcl-1 protein(2025)

  期刊：Cancer Cell International

  DOI：10.1186/s12935-025-03825-8

  影响因子：5.3

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• A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells(2025)

  期刊：MOLECULES

  DOI：10.3390/molecules30112347

  影响因子：4.2

  相关产品： H9c2(2-1) Cells Line, HL-60 Cells Line, MV-4-11 Cells Line

• Evaluation of anti-leukemic activity and underlying mechanisms of the novel GSPT1 degrader AB138 in acute myeloid leukemia(2025)

  期刊：INVESTIGATIONAL NEW DRUGS

  DOI：10.1007/s10637-025-01541-8

  影响因子：3

  相关产品： NB4 Cells Line, MV-4-11 Cells Line

• Two?New Cembranoids?from the Soft Coral Sinularia sp. with Antioxidant Activity(2025)

  期刊：CHEMISTRY & BIODIVERSITY

  DOI：10.1002/cbdv.202500141

  影响因子：2.3

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• Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury(2024)

  期刊：JOURNAL OF MEDICINAL CHEMISTRY

  DOI：10.1021/acs.jmedchem.3c02441

  影响因子：7.3

  相关产品： RAW 264.7 Cells Line, MV-4-11 Cells Line

• Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway(2024)

  期刊：Journal of Cancer

  DOI：10.7150/jca.89243

  影响因子：3.9

  相关产品： Fetal Bovine Serum, MV-4-11 Cells Line, U-87 MG Cells Line

• Targeting cytohesin-1 suppresses acute myeloid leukemia progression and overcomes resistance to ABT-199(2023)

  期刊：ACTA PHARMACOLOGICA SINICA

  DOI：10.1038/s41401-023-01142-2

  影响因子：8.2

  相关产品： MV-4-11 Cells Line

• Design, synthesis, activity and molecular dynamics studies of 1,3,4-thiadiazole derivatives as selective allosteric inhibitors of SHP2 for the treatment of cancer(2023)

  期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

  DOI：10.1016/j.ejmech.2023.115585

  影响因子：6.7

  相关产品： MV-4-11 Cells Line, NCI-H358 Cells Line, A549 [A-549] Cells Line, MDA-MB-468 Cells Line

• Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171(2023)

  期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

  DOI：10.1016/j.ejmech.2023.115514

  影响因子：6.700

  相关产品： MV-4-11 Cells Line

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