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MIP-1γ/CCL9, Mouse, Recombinant-1

英文名称：MIP-1γ/CCL9, Mouse, Recombinant

货号：GPCK232

价格： ￥11880.00 ￥2280.00 ￥780.00 ￥17280.00

规格：
500μg 50μg 10μg 1mg
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产品信息

产品形态 粉末
产品规格 500μg / 50μg / 10μg / 1mg
表达宿主 E.coli
序列信息 Gln22-Gln122
检索号 P51670
分子量 11.6 kDa
表观分子量 15 kDa
纯度 > 90% as determined by reducing SDS-PAGE.
内毒素 < 0.1 EU/μg
制剂 Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 300 mM NaCl, pH 8.0.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 C-C Motif Chemokine 9 (CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of Chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and Chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity Receptor，it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its Receptor CCR1 (the most abundant Chemokine Receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
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