
英文名称:IL-6Rα/CD126, Human, Recombinant
货号:GPCK202
价格: ¥11880.00 ¥2280.00 ¥780.00 ¥17280.00
规格:
500μg
50μg
10μg
1mg
产品详情
产品信息
产品规格 | 500μg / 50μg / 10μg / 1mg |
表达宿主 | Human Cells |
序列信息 | Leu20-Asp358 |
检索号 | P08887 |
分子量 | 38.9 kDa |
表观分子量 | 60-75 kDa |
标签 | C-6His |
纯度 | > 95% as determined by reducing SDS-PAGE. |
内毒素 | < 0.1 EU/μg |
制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
运输条件 | Ambient temperature or ice pack. |
有效期 | 12个月 |
背景介绍 | Interleukin 6 is a potent pleiotropic Cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the Receptor for Interleukin 6 Cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 Receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this Receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. |
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