FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
货号:GFH1132UC
价格: ¥1260.00 ¥420.00
产品详情
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Clone No. HostRat
ReactivityMouse
IsotypeRat IgG2b, κ
ConjugateFITC
Concentration0.5 mg/mL
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
相关文献
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期刊:Nature Communications
DOI:10.1038/s41467-024-53010-0
影响因子:14.7
相关产品: FITC Anti-Mouse CD274 Antibody, RPMI-1640 Medium, STR Identification, 0.25% Trypsin Solution, STR Identification, Phosphate Buffer (PBS, 1 ×)
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期刊:JOURNAL OF CONTROLLED RELEASE
DOI:10.1016/j.jconrel.2024.02.029
影响因子:10.5
相关产品: PerCP Anti-Mouse CD11c Antibody, FITC Anti-Mouse CD274 Antibody