请输入关键词!

Elab Fluor® 488 Anti-Human CD197/CCR7 Antibody[G043H7]

说明书
  • Elab Fluor® 488 Anti-Human CD197/CCR7 Antibody[G043H7]-1
Elab Fluor® 488 Anti-Human CD197/CCR7 Antibody[G043H7]-1

货号:GFH1159L

价格: ¥3168.00 ¥1296.00 ¥4680.00

规格:
100 Tests 20 Tests 100 Tests × 2
产品详情
Background

CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.

Alternate Names

EBI1EVI1;CCR-7;CDw197;CMKBR7

Swissprot

P32248

Clone No.

G043H7

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG2a, κ

Conjugate

Elab Fluor®488

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

产品结果图

Elab Fluor® 488 Anti-Human CD197/CCR7 Antibody[G043H7]-产品结果图-1

×
确定