FITC Anti-Human CD8a Antibody[HIT8a]

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

CD8Leu-2Ly-2;CD8;CD8 antigen alpha po;CD8 antigen alpha polypeptide;CD8A;Leu;Leu2;MAL;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu;T-lymphocyte differentiation antigen T8/Leu-2;T8;alpha polypeptide (p32);p32

P01732

HIT8a

Mouse

Human

Mouse IgG1, κ

FITC

5 μL/Test

FCM

Monoclonal

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

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