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FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

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  • FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]-1
FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]-1

MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).

货号:GFH1229C

价格: ¥2088.00 ¥792.00 ¥3168.00

规格:
100 Tests 20 Tests 100 Tests × 2
产品详情
Background

Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

Alternate Names

PD1;PDCD1;Protein PD-1;hPD-1

Swissprot

Q15116

Clone No.

EH12.2H7

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG1, κ

Conjugate

FITC

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

产品结果图

MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]-产品结果图-1

MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).

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