FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]
MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).
货号:GFH1229C
价格: ¥2088.00 ¥792.00 ¥3168.00
产品详情
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Alternate NamesPD1;PDCD1;Protein PD-1;hPD-1
Swissprot Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG1, κ
ConjugateFITC
Concentration5 μL/Test
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).
MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).
相关文献
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